NAD+ IV Therapy: Cellular Energy Delivered Directly to Your Bloodstream
Nicotinamide adenine dinucleotide — the coenzyme at the center of cellular energy production — delivered via IV infusion for maximum bioavailability.
Book Your Free ConsultationMedically reviewed by Dr. Jamie Lynn Jaqua, MD · Board-Certified Family Medicine · Vitality Texas
Delivery method note: This page covers NAD+ as an IV infusion administered in-clinic. For subcutaneous injectable NAD+ for home use, see our injectable NAD+ program.
The Science of NAD+ IV Infusion
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell. It is essential for mitochondrial energy production, DNA repair, cellular signaling, and the activity of sirtuins — proteins linked to cellular health and longevity research. NAD+ levels decline with age, contributing to the metabolic and cognitive changes associated with aging (Rajman et al. Cell Metabolism. 2018;27(3):529–547).
IV delivery achieves plasma NAD+ concentrations significantly higher than oral supplementation or subcutaneous injection in a single session. The trade-off is session time — NAD+ IV infusions are administered slowly (typically 60–120 minutes) to minimize any transient flushing or discomfort. For patients seeking the highest-concentration single session, IV is the preferred route.
Vitality Texas also offers subcutaneous injectable NAD+ for at-home daily use (see our injectable NAD+ program). Many patients combine both modalities — periodic IV sessions for peak cellular loading and daily injectable NAD+ for ongoing maintenance. Dr. Jaqua will advise on the protocol that best fits your goals and schedule.
What NAD+ IV Therapy Supports
Cellular Energy
- Supports ATP production in mitochondria
- Patients report improved energy and mental clarity
- Cellular energy supports recovery from physical and cognitive demand
Cognitive Support
- NAD+ is essential for neuronal energy metabolism
- Studied in context of brain aging and cognitive function research
- Physician-supervised protocol for patients reporting brain fog or mental fatigue
Metabolic Function
- NAD+ supports fat metabolism and insulin signaling pathways
- Complements GLP-1 and weight management programs for cellular support
- Studied in context of metabolic health and aging research (Rajman et al., 2018)
Your NAD+ IV Protocol
Consultation
Dr. Jaqua reviews your health history and goals. NAD+ IV is appropriate for patients seeking cellular energy support, cognitive clarity, or metabolic optimization.
Slow IV Infusion
60 to 120 minutes. NAD+ must be infused slowly to minimize transient flushing or chest tightness — normal physiological responses that resolve when the infusion rate is lowered.
Immediate Cellular Loading
IV delivery achieves peak plasma NAD+ concentration in a single session — higher than subcutaneous injection or oral supplementation can achieve acutely.
Ongoing Protocol
Most patients start with 1–2 IV sessions, then transition to injectable NAD+ for daily maintenance between sessions. Dr. Jaqua will design your protocol.
Good Candidates for NAD+ IV Therapy
NAD+ IV therapy at Vitality Texas is appropriate for patients experiencing persistent fatigue, brain fog, or metabolic slowdown that does not have a single identifiable cause. It is also used by patients seeking proactive cellular support in the context of healthy aging.
NAD+ IV is distinct from our injectable NAD+ subcutaneous program. IV delivers the highest plasma concentration per session; injectable NAD+ is more practical for daily ongoing maintenance. Both programs are physician-supervised by Dr. Jaqua.
Compliance note: At Vitality Texas, we frame NAD+ therapy as supporting cellular energy and metabolic function. We do not make anti-aging outcome guarantees.
NAD+ IV Therapy Questions & Answers
Everything you need to know about NAD+ IV infusion at Vitality Texas.
References
- Rajman L, Chwalek K, Sinclair DA. Therapeutic potential of NAD-boosting molecules: the in vivo evidence. Cell Metabolism.2018;27(3):529–547.
Ready to Start NAD+ IV Therapy?
NAD+ IV therapy starts with a physician consultation with Dr. Jaqua. Book your free consultation today.
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